One Zyme
One Zyme / Platform Solutions / Search & Evaluation Intelligence
Discover & Evaluate
Search & Evaluation Intelligence

Best-in-class AI intelligence for S&E.

Find, prioritize, and evaluate external innovation across global scientific, clinical, regulatory, financial, patent, deal and conference signals, all in one evidence-grounded intelligence workflow.

1
Halifax Bio · HFX-2104
High relevance
0.94
2
Meridian Therapeutics
Emerging catalyst
0.89
3
Hangzhou Immuno · HZ-880
China-first competitor
0.86
4
Stealth · undisclosed
Stealth funding signal
0.81

OneZyme.ai has been a highly valuable platform for business development, R&D, and competitive intelligence workflows, particularly in helping synthesize complex biotech and pharma landscapes with a high degree of accuracy and practical relevance. Beyond the strength of the platform itself, the One Zyme team has been exceptionally responsive, thoughtful, and open to feedback, making it clear that they are building with real-world BD, strategy, and executive decision-making needs in mind. I have found the tool to be a strong resource for accelerating insight generation while maintaining the level of rigor required in biotech and pharma.

Kristine Yu VC/BD and Former VP of Business Development at Arbor Biosciences
How it works

The process to build an evidence-backed opportunity view.

01, Strategic Criteria Engine

Interprets your team's priorities

Therapeutic area, indication, target, mechanism, modality, stage, geography, ownership status, TPP criteria, and deal preferences, parsed from one natural-language brief.

02, Global Evidence Retrieval

Searches every relevant source

Scientific literature, clinical trials, conference data, patents, regulatory filings, SEC/CDE/FDA sources, company websites, venture/grant financing, licensing, M&A, and uploaded materials.

03, Biopharma Entity Resolution

Resolves the relationships

Sponsors, assets, targets, mechanisms, indications, investigators, trials, regulatory events, publications, patents, financings, licensing, M&A, and corporate structures, collapsed into canonical records.

04, Strategic Fit Ranking

Ranks against your strategy

Scientific rationale, clinical stage, differentiation, financing, partnerability, competitive intensity, China relevance, and customer-specific priorities, scored and sorted.

05, Source-Grounded Synthesis

Writes the evidence-backed view

Concise analysis with clickable references, supporting rationale, open questions, and recommended next steps with every claim cited.

06, Workflow Activation

Turns findings into action

Opportunity briefs, watchlists, monitoring alerts, conference target lists, diligence memos, board-ready summaries, and CRM-ready outputs.

Criteria engineparsing
"Find Phase 1/2 autoimmune assets with differentiated mechanisms and partnerability in 12–18 months."
AutoimmunePhase 1/2Differentiated MOATranslationalPartnerable12–18 mo
Evidence retrievalstreaming
Clinical trials
Patents
Regulatory filings
Publications
Financing / deals
China data
Entity resolutionmerging
"Halifax Bio Inc."
Halifax Bio
"Halifax Biosciences"
↳ same entity
HFX-2104 · "OZ-A"
Asset record
NCT05892341
↳ linked trial
Strategic fit rankingscoring
01
Halifax Bio · HFX-2104
IL-23 · Ph II · partnerable
0.94
02
Hangzhou Immuno · HZ-880
TYK2 · Ph II · CN
0.89
03
Meridian Therapeutics
JAK1 · Ph I · US
0.82
Source-grounded synthesiswriting
NCT05892341USPTO·12/847,221Nature·2026.04CDE·CXHL2400321SEC·8-K·Q1
Workflow activationready
Data foundation

Built on better biopharma data, not generic web search.

One Zyme assembles fragmented public, private, structured, and unstructured data into a continuously updated, source-cited intelligence layer.

One ZymeBiopharma Evidence Graph

Deep China coverage built into the evaluation workflow.

China is now one of the most important sources of emerging biopharma innovation. One Zyme brings China visibility directly into search and evaluation, surfacing assets, competitors, and signals traditional databases miss.

China Intelligence layer
Ranked autoimmune assets● China layer active
01
Halifax Bio · HFX-2104
IL-23 · Ph II · US
0.94
02
Hangzhou Immuno · HZ-880 CN
TYK2 · Ph II · CDE priority review
0.91
03
Meridian Therapeutics
JAK1 · Ph I · US
0.82
04
Beijing Helix · BHX-7 CN
ROR-γt · Ph I · IND accepted
0.79
05
Suzhou Biologics CN
IL-17 bispecific · preclinical
0.74
Preclinical visibility

Spot programs before they reach Western awareness.

e.g. published MOA + early in-vivo data
IND & trial activity

Track IND filings and active China trials in real time.

e.g. CDE acceptance · ChiCTR registration
Regulatory acceleration

Catch priority review and breakthrough designations.

e.g. priority review granted · BTD
Patent coverage

Map CNIPA families and cross-border filings.

e.g. CN116873104 · PCT entry
Corporate structure

Resolve subsidiaries, JVs, and related parties.

e.g. parent ↔ subsidiary ↔ licensee
Partnerability

Assess licensing readiness and existing relationships.

e.g. ex-China rights available

Comprehensive China visibility where others see fragments.

One Zyme connects trial, patent, financing, discovery, preclinical and even hidden company structure signals across China's biopharma landscape so search and evaluation teams can identify emerging assets before the market catches up.

BeijingZhongguancun
ShanghaiZhangjiang
SuzhouBioBAY
HangzhouBinjiang
WuhanOptics Valley
ChengduTianfu
GuangzhouGIBH
ShenzhenNanshan
One Zyme · Depth in China Every cluster. Every signal. Every day. Live · streaming across 18+ China sources
Example outputs

From question to decision-ready output.

One Zyme turns weeks of fragmented research into a single integrated BD workflow.

With One Zyme 5 steps · minutes → executive-ready BD deck
01 · Search

Top-of-funnel TA search

Global scan across scientific, clinical, regulatory, financial, patent, deal, and conference sources.

3,412 hits→ 124 in scope
02 · Prioritize

Prioritized deep dive

Strategic-fit ranking of the most relevant assets and companies for your TPP.

14 priorities0.94 fit
03 · Science

Scientific deep dive

Mechanism, data, and translational rationale, every claim source-grounded.

38 citations7 US / 7 CN
04 · Landscape

Competitive landscape & transactions

Full view of competing assets, trials, IP, financing, plus in-depth deal-comp analysis with precedents, structures, and valuation context.

26 competitors14 deal compscited
05 · Deck

Polished BD deck

Enterprise-ready presentation assembled from the cited analysis above.

12 slidesCBO-ready
Before One Zyme 11+ steps · weeks → a draft, eventually
CortellisSearch legacy database for a long list of assets
CitelineSearch another database for a long list of trials
15 browser tabsCross-check scattered sources for the competitive landscape
China gapPiece together China and emerging-market visibility
Slack threadAsk internal team members for missing context
ReconcileReconcile conflicting asset and trial information
FilterManually assess which assets are actually relevant
TransactionsPull comparable deals from Cortellis Deals Intelligence and reconcile against your thesis
DocBuild a thesis from disconnected evidence
Copy-pasteCopy findings into slides
FormatRewrite and reformat the deck
QAManually assemble an executive presentation
Build TPPs on demand

A target product profile for every asset you see, in minutes.

Drop in an asset. One Zyme drafts your team's TPP against it, every field grounded in cited evidence, every comparison made against the assets and competitors that matter.

Your TPP template

in scope
Section progress 0 / 8
Indication & settingqueued
Mechanism & modalityqueued
Efficacy barqueued
Safety profilequeued
Manufacturing / logisticsqueued
Competitive framequeued
Differentiation hookqueued
Strategic framequeued
CART
CD19 CAR-T · r/r oncology
Asset class · next-gen autologous
FDA labels ClinicalTrials.gov SEC 10-Q Conf. data CDE
0
Sources cited
0
Comparators
0
Runtime
TPP CD19 CAR-T · v0.1 · drafting…
One Zyme is writing
01 Indication & setting
02 Mechanism & modality
03 Efficacy bar
04 Safety profile
05 Manufacturing / logistics
06 Competitive frame
07 Differentiation hook
08 Strategic frame
drafted in under 5 min · every claim cited
Templated

Lock in your team's TPP fields once.

Indication, MoA, efficacy bar, safety, mfg, comps, differentiation, strategy, your structure, every time.

Auto-filled

One Zyme drafts every field against the asset you choose.

From the FDA label to ChiCTR registrations to conference posters, fields populate with sourced answers.

Comparable

Side-by-side comps, in the same workflow.

Spin up TPPs for every comparable asset, and rank them against your team's strategic criteria.

A new workflow model

From manual database searches to AI-native asset evaluation.

With Cortellis
With One Zyme
Run keyword searches across multiple databases
Ask strategic, criteria-rich questions in natural language
Pull static records into spreadsheets
Generate customized, ranked, evidence-linked asset shortlists
Reconcile companies, assets, trials, patents, deals, and filings by hand
Resolve assets, companies, mechanisms, indications, trials, IP, financings, and corporate structures automatically
Analyze China separately, or skip it
Surface China-originated assets and signals in the same workflow
Build PowerPoint summaries manually
Produce source-backed briefs, TPP-matched lists, and BD-ready decks
Point-in-time, often stale
Continuously updated as new evidence appears
User does the analytical heavy lifting
Agents retrieve, compare, rank, summarize, and explain

Find the right asset, first.

Get a strategic briefing tailored to your therapeutic areas, TPP criteria, competitor set, China visibility needs, and external innovation priorities.