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Discover & Evaluate · Solution 03
New Product Planning Intelligence

New product planning that turns a crowded market into a launch plan.

Build the competitive set, benchmark your target product profile against the standard of care and the pipeline, sequence the right indications, and time it all around the catalysts that will move the market.

Where does our oral, gut-selective candidate win against the IBD standard of care?
Target product profile · vs. standard of careauto-benchmarked
Efficacy · endoscopic remission Advantage
Route · oral vs. IV biologic Advantage
Safety · selectivity profile Advantage
Dosing burden At parity
0.94 Differentiation score, strongest defensible wedge in the comparable set.
The shift

Build a plan that changes and updates automatically in response to market dynamics.

The problem

Your plan is out of date the moment it's built.

A launch plan is a snapshot: competitive sets built by hand, TPP benchmarks in a spreadsheet, indication and reimbursement signals scattered across tools, and a catalyst calendar that's stale the week after it's made.

The market keeps moving, but the plan doesn't. Keeping it current means painful manual re-work every quarter, and in between, you're falling behind.

What One Zyme does

A living plan that keeps itself current.

Build a new product plan on current market conditions, then let One Zyme track the dynamics that matter, competitive moves, trial catalysts, reimbursement and pipeline shifts, and update your plan automatically as they change.

No painful quarterly re-work, no falling behind. The plan stays live, and every claim traces to its source.

Competitive set & TPP

Benchmark your target product profile against the whole field at once.

One Zyme assembles the comparable assets, approved and in development, and scores your candidate against them attribute by attribute, so the differentiation case is grounded in evidence, not assertion.

Benchmarking approved + pipeline · entity-resolved · cited comparable assets · 62 in set
Attribute
Your candidateoral · gut-selective TL1A
Incumbent biologicanti-IL-23 · IV
Oral advancedTYK2 · oral
Emerging rivalα4β7 integrin · oral
Efficacyendoscopic remission
Lead
Strong
Parity
Parity
Route & convenienceoral vs. infusion
Oral
IV only
Oral
Oral
Safety & selectivityclass signals
Selective
Parity
CV watch
Parity
Dosing burdenmaintenance
Low
Clinic
BID
Parity
IP defensibilitypatent runway
Long
Strong
Crowded
Thin
Differentiationvs. standard of care
Clear
Moderate
Moderate
Modest
One Zyme's read Your candidate leads on efficacy, oral convenience, and safety, the defensible wedge is an oral, gut-selective profile positioned directly against IV incumbents.
0Attributes scored
0Comparable assets
Labels + trialsEvidence base
100%Claims cited
Indication sequencing

Sequence the indications that build the franchise.

Not every indication deserves to be first. One Zyme scores each candidate indication on unmet need, competitive timing, trial feasibility, and reimbursement path, then recommends the launch-and-expand sequence that compounds.

Lead indication 1
Launch
Moderate-to-severe ulcerative colitis
Deep unmet need behind biologics, the cleanest efficacy story, and a reimbursement path already paved by incumbents.
0.94
Fit
2
Expansion 01
Crohn's disease
Mechanistic read-through from UC, a large addressable population, and trial infrastructure you can reuse.
0.86
Fit
3
Expansion 02
Pediatric IBD
High need, thin competition, and an oral, selective profile that fits where injectables struggle.
0.78
Fit
4
Watchlist
Chronic pouchitis
A defensible niche with almost no approved options, strong fit, but smaller and best timed after the core franchise lands.
0.66
Fit

How the sequence is built

Each indication is scored on four weighted dimensions, then ordered to maximize the franchise, not just the first approval.

Unmet need depth
Burden, remission gaps, and treatment-failure populations, grounded in cited evidence.
Competitive timing
Where rivals are heading and which windows stay open by the time you arrive.
Trial feasibility
Endpoint precedent, enrollment dynamics, and reusable infrastructure across indications.
Reimbursement path
Payer precedent and access dynamics that shape real-world uptake.
Launch catalyst calendar

Plan around the catalysts that will move the market.

Competitor readouts, regulatory decisions, guideline updates, and payer cycles all reshape a launch window. One Zyme maintains the catalyst calendar for your space and keeps it current as the landscape shifts.

Tracking readouts · FDA/EMA/NMPA actions · guidelines · payer cycles catalysts in window · 18
Q3 2026Near term
Incumbent anti-IL-23 Phase III readout
A positive maintenance result would raise the efficacy bar your TPP is benchmarked against.
Competitor readout · resets efficacy bar
Q4 2026Near term
FDA action date · oral TYK2 rival
The first oral advanced therapy to clear would reshape the convenience narrative for the class.
Regulatory decision · first oral in class
Q1 2027Your milestone
Your Phase II topline
The positioning checkpoint, where the differentiation case is confirmed or re-cut against the field.
Internal catalyst · positioning checkpoint
Q2 2027Mid term
Major society guideline update
A revised treatment algorithm can move oral therapies earlier in the line, directly affecting addressable population.
Guideline shift · moves line of therapy
Q3 2027Mid term
China NMPA approval · regional rival
An ex-US approval changes global pricing reference points and partnering dynamics for the asset.
Ex-US dynamics · pricing & partnering
Q4 2027Access
Payer formulary cycle
The access window that determines real-world uptake, and where contracting strategy has to be ready in advance.
Payer cycle · access window
Positioning & differentiation

Find the position that's defensible, and still needed.

One Zyme plots every comparable asset by differentiation and unmet need at once. The right position isn't just the open space, it's the open space where patients still have no good option.

Positioning map · IBDdifferentiation × unmet need
Unmet need →
Defensible position · high need · differentiated
Oral gut-selective · 1L moderate-severe
Oral selective · pediatric IBD
Crowding of comparable positioning →
Open / differentiatedCrowded
High-fit position Crowded Comparable assets
Positioning shortlistranked by fit
1
Oral gut-selective · 1L moderate-severe
need 0.92 · crowding 0.22
0.94
2
Oral selective · pediatric IBD
need 0.81 · crowding 0.34
0.86
3
Maintenance convenience · post-biologic
need 0.74 · crowding 0.45
0.78
4
Niche · chronic pouchitis
need 0.68 · crowding 0.30
0.71
How the plan comes together

Three moves from market to plan.

01

Build the competitive set

Assemble every comparable asset, trial, and label, approved and in development, resolved to the same entities and continuously refreshed.

02

Benchmark the TPP

Score your profile against the standard of care and the pipeline, attribute by attribute, to surface the defensible differentiation case.

03

Sequence & time the plan

Rank indications by need and feasibility, then time launch and expansion around the catalysts that will move the market.

A new workflow model

No more legacy databases.

With Cortellis & spreadsheets
With One Zyme
Build the competitive set by hand in slides, and rebuild it every quarter
A live competitive set of approved and pipeline assets, resolved and refreshed
TPP benchmarks trapped in one analyst's spreadsheet
Attribute-by-attribute TPP scoring against the whole field, every claim cited
Indication attractiveness argued from gut feel and a few decks
Indications scored on need, timing, feasibility, and reimbursement
A catalyst calendar in a shared doc, stale within a week
A maintained catalyst calendar that updates as the landscape moves
Positioning decided without a clear view of unmet need
A positioning map of differentiation × unmet need with a ranked shortlist
A static plan that's a snapshot no one fully trusts
A living plan you can interrogate, traced to source at every step

Powered by the One Zyme intelligence layer.

Every planning workflow runs on the same agents, data, and evidence trail that power the rest of the platform.

Explore Models & Data →
Global biopharma data layer
Scientific document intelligence
China intelligence layer
Biopharma knowledge graph
Agentic research engine
Evidence & citation layer
Deals & transactions layer

Build the launch plan on evidence, not assumptions.

Get a strategic briefing tailored to your asset, target product profile, and indication priorities.