One Zyme
One Zyme / Models & Data
The infrastructure beneath every answer
Models & Data

Multiple models, one deep biopharma context.

One Zyme isn't a single model with a search box bolted on. It routes every question to the model best suited to the job, and because we do only biopharma, each one runs on context no general-purpose system can match.

Model router
Domain RetrievalEmbeddings
Biomedical embeddings tuned on trials, patents & literature, not generic web text.
Document ExtractionParsing
Pulls endpoints, doses, and outcomes from PDFs, filings & posters.
Entity ResolutionLinking
Collapses messy aliases into canonical companies, assets & targets.
Reasoning & SynthesisAnalysis
Frontier reasoning models compose cited, decision-ready answers.
Cross-Lingual (China)Translation
Reads Chinese-language registries, CDE filings & corporate sources natively.
Ranking & ScoringPrioritization
Orders results by strategic fit, novelty, stage & competitive intensity.
The architecture

Four layers, each purpose-built, all working in concert.

From the models at the bottom to the reports and agents at the top, every layer is engineered specifically for biopharma. Explore each one.

Model orchestration

A range of models, orchestrated as one system.

No single model is best at everything. One Zyme runs a portfolio of specialized and frontier models, each doing the part of the job it's best at, coordinated into a single pipeline behind one interface.

Understand

Query understanding

Parses intent, entities, and scope out of a natural-language question.

Retrieve

Domain retrieval

Biomedical embeddings pull the exact trials, patents, filings, and literature that matter.

Reason

Multi-model reasoning

Specialized and frontier models analyze the evidence in parallel.

AnalysisExtractionCross-lingual
Verify

Cross-verification

Models check one another's work and reconcile every finding against the sources.

Synthesize

Cited synthesis

Findings assembled into a decision-ready, fully source-cited answer.

Depth of context

Because we do only biopharma, we build context others can't.

A general-purpose model sees your question as text. One Zyme sees it through layers of biomedical structure, the ontologies, graphs, and schemas that let it reason like a domain expert.

General-purpose AI Shallow

Public web textWhatever was on the open internet at training time.
Generic embeddingsTreats "ADC" the drug and "ADC" the acronym alike.
No clinical, regulatory, or China-native grounding.
Plausible-sounding answers, no evidence trail, no biopharma structure.

One Zyme Exceptionally deep

Biomedical ontologiesMeSH, MedDRA, ATC, ICD & target/pathway vocabularies.
Asset & company graphAssets, sponsors, mechanisms, modalities & ownership linked.
Trial & regulatory schemasPhases, endpoints, designations & filing types modeled natively.
Synonym & alias disambiguationCode names, brand names & abbreviations resolved in context.
China biopharma corpusChinese-language registries, CDE filings & corporate records.
Evidence & citation layerEvery fact tied back to a clickable, dated source.
Answers that read like an analyst's, structured, source-cited, and aware of how biopharma actually works.
The data layer

Deeply integrated data, not a generic web index.

One Zyme continuously assembles global and China-native sources, clinical, scientific, regulatory, financial, and corporate, into one structured, source-cited intelligence layer your team can query directly.

Data sources Auto-select
US Clinical Trials (ClinicalTrials.gov)540K
China Trials (ChiCTR · CDT)88K
EU Clinical Trials (CTIS)61K
UK Clinical Trials (ISRCTN)24K
openFDA (FDA drug data)live
China CDE · NMPA approvalslive
Patents36M
Science journals34M
SEC filingslive
Mergers & acquisitionslive
Fundings (venture / grant)live
Open Targetslive
Conference presentationslive
China company landscapelive
People directorylive
Your uploaded filesprivate

Clinical Trials

Continuously updated
Trial IDTitleRegistryPhasePublished
ChiCTR2600126786 Vibecotamab in Locally Advanced or Metastatic Squamous Cell Carcinoma of the Urinary Tract ChiCTR Phase 2 2026-06-16
NCT06721044 Bispatamig ADC in Relapsed/Refractory B-cell Malignancies CT.gov Phase 1/2 2026-06-15
ChiCTR2600126802 Anti-Claudin18.2 CAR-T for Advanced Gastric Adenocarcinoma ChiCTR Phase 1 2026-06-14
2026-501882-31 TYK2 Inhibitor in Moderate-to-Severe Plaque Psoriasis CTIS Phase 3 2026-06-13
NCT06718903 GLP-1 / GIP Co-agonist in Obesity With Cardiometabolic Risk CT.gov Phase 2 2026-06-12
Clinical

Global & China trial registries, protocols, endpoints, sponsors, and investigators.

700K+ trials
Scientific

Peer-reviewed literature, preprints, conference abstracts, and posters.

34M+ papers
Regulatory

FDA, EMA, NMPA & CDE filings, approvals, designations, and priority reviews.

FDA · CDE · NMPA
Financial & corporate

SEC disclosures, fundings, M&A, licensing, pipelines, and company structure.

36M+ patents
System of context

Fragmented signals, resolved into one canonical record.

The same company appears a dozen ways across sources. One Zyme links them, so a trial in Suzhou, a patent family, and an SEC disclosure all point to the same asset.

ChiCTR"Halifax Biosciences (Suzhou) Co."
SEC"Halifax Bio, Inc."
Patent"HFX-2104 · compound OZ-A"
Press"Halifax Bio (formerly Hifax Tx)"
Trial"NCT05892341 · sponsor: Halifax"
Halifax Bio Canonical record
Lead asset
HFX-2104
Target
IL-23
Stage
Phase 2
HQ
Suzhou, CN
Linked evidence
Evidence & citation

Every answer traces back to a source you can open.

The models do the reasoning; the evidence layer keeps them honest. Each claim carries a clickable, dated citation, built for the rigor biopharma decisions demand.

Grounded, not generated

Answers are assembled from retrieved evidence, not produced from a model's memory and hoped to be right.

Citations on every claim

Each statement links to the exact trial, filing, patent, or paper it came from, with the date attached.

Fresh, dated, auditable

Sources are continuously refreshed and timestamped, so you can see exactly how current the evidence is.

See the models and data work on your questions.

Get a strategic briefing tailored to your therapeutic areas, competitors, and watchlists, and watch the platform reason over real biopharma evidence.